Multiplayer tower defense games for PC/Windows with 2-player support

Plants vs Zombies: Garden Warfare

Players: 0 local, 4 online

Cubemen 2

Players: 0 local, 6 online

Towers of Altrac

Players: 0 local, 4 online

Particula

Players: 0 local, 3 online

Duo Defenders - Tower Defense

Players: 2 local, 0 online

Bunker Defense

Players: 0 local, 4 online

Dungeon Defenders Eternity

Players: 0 local, 4 online

Orcs Must Die! Unchained

Players: 0 local, 3 online

D-Corp

Players: 4 local, 0 online

Gensokyo Defenders

Players: 0 local, 2 online

Versus

Players: 0 local, 4 online

Hell Warders

Players: 0 local, 4 online

Defenders of the Fallen Island

Players: 0 local, 4 online

Sky Fleet

Players: 0 local, 4 online

Elementowers

Players: 2 local, 2 online

Garda

Players: 5 local, 0 online

CastleStorm II

Players: 2 local, 0 online

Harvest Hero Origins

Players: 2 local, 0 online

Dungeon Defenders: Going Rogue

Players: 0 local, 4 online

The Last Friend

Players: 2 local, 0 online

Defenders: Survival and Tower Defense

Players: 0 local, 4 online

Warstone TD

Players: 0 local, 2 online

SENTRY

Players: 0 local, 2 online

Private Property

Players: 0 local, 4 online

Blackout!!

Players: 2 local, 0 online